Ketamine & spravato® infusion in castle rock, co

Rapid-relief depression treatment
that meets you where you are

What Is Ketamine Therapy?

Ketamine therapy is a cutting-edge mental health treatment that uses low-dose ketamine to provide fast-acting relief for depression, suicidality, anxiety, PTSD, and other mood-based conditions, often offering hope when traditional medications and therapy haven’t worked. Ketamine enhances neuroplasticity, the brain cells’ ability to form new connections with one another. It also demonstrates the ability to repair neurons that have atrophied. Treatment follows a structured schedule over several weeks, and many patients begin noticing changes within 24 hours. This treatment taps into brain pathways that standard antidepressants do not, giving patients a chance for rapid relief and renewed perspective.

At Harmony Neurocare, ketamine therapy is offered alongside other advanced modalities like Deep TMS, forming part of our Integrative Psychiatry Colorado approach to comprehensive mental health care.

SPRAVATO® TREATMENT AT HARMONY NEUROCARE

A supervised, FDA-approved option for treatment-resistant depression

SPRAVATO® is an FDA-approved esketamine nasal spray designed for adults with treatment-resistant depression who haven’t found relief with traditional antidepressants. It works through glutamate pathways rather than serotonin, creating faster shifts in mood and thought patterns. Each dose is administered in-clinic under provider supervision so you can feel supported and monitored throughout the process.

During your visit, you self-administer SPRAVATO® with guidance, then rest comfortably in a private room while our team observes your response. Treatment follows a structured schedule over several weeks, and many patients begin noticing changes early on. SPRAVATO® can be integrated with therapy, medication management, or Deep TMS as part of a personalized plan designed to support long-term healing.

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HOW KETAMINE THERAPY WORKS

A guided, medically supervised process designed
for rapid relief and long-lasting change.

Ketamine therapy uses low-dose ketamine to shift brain activity in ways traditional medications cannot. Treatments are delivered safely in our clinic under continuous monitoring, and many patients begin noticing relief within hours or days.

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Your Ketamine Treatment Journey

STEP 1: INITIAL CONSULT

Your journey begins with a comprehensive evaluation that explores your symptoms, history, and treatment goals. Together, we determine whether IV ketamine infusion, SPRAVATO®, or assisted psychotherapy is the most effective path forward.

Many clients leave this conversation feeling relieved to finally have a treatment option that offers rapid relief.

STEP 2: PREPARATION AND SAFETY REVIEW

Before your first session, your provider walks you through the entire process, discusses safety measures, and answers any questions. You receive instructions about how to prepare and what to expect during treatment.

This preparation helps most people feel grounded and confident going into their first session.

STEP 3: TREATMENT SESSION

Ketamine is administered slowly and safely, either by IV infusion, SPRAVATO® nasal spray, or within a therapeutic session. You remain awake and supported while your care team monitors you throughout.

Many people describe this stage as calming or introspective, with sensations fading shortly after the session ends.

STEP 4: IMMEDIATE AFTERCARE

After your treatment, you spend a short period in a quiet, supervised space while the acute effects settle. Your team checks your vital signs, ensures your comfort, and provides guidance for the rest of your day.

Most individuals feel mentally clearer within a few hours and often notice subtle emotional shifts soon after.

STEP 5: CONTINUED SESSIONS AND PROGRESS MONITORING

Ketamine therapy typically unfolds over a series of sessions spaced across several weeks. Your provider adjusts dosing and frequency based on your progress and helps track improvements in mood, clarity, and overall functioning.

Lots of clients report noticeable improvements after their first session.

STEP 6: ONGOING ASSESSMENTS

We regularly check in with scaling metrics to scientifically track your depression or anxiety scores, making sure the treatment protocol aligns with your goals and progress.

This keeps your care grounded in tangible evidence.

STEP 7: INTEGRATION THERAPY

Optional integration sessions help you process the insights and experiences from your ketamine therapy, grounding the rapid changes into lasting shifts in perspective and mood.

Patients often find these sessions maximize their clinical outcomes.

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How Ketamine Therapy
Complements Deep TMS

While Deep TMS works by stimulating underactive brain regions over repeated sessions, ketamine therapy offers a different route — rapidly inducing neurochemical shifts that can jumpstart healing. Together, they offer complementary pathways: TMS supports long-term brain rewiring, and ketamine can offer acute relief and reset when symptoms are urgent or severe.

This dual-approach is part of Harmony Neurocare’s commitment to comprehensive, integrative mental health care — giving patients multiple tools for hope and healing.

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Frequently Asked Ketamine & SPRAVATO® Questions

SAFETY, EXPERIENCE, AND RESULTS

Yes. When administered under medical supervision in a clinical setting, ketamine therapy has a strong safety profile. Side effects are usually temporary and are monitored closely by your care team.
Many people describe the experience as mildly dissociative or dreamlike. These sensations occur during or shortly after treatment and typically fade within a couple of hours.
Some individuals notice improvement within hours or by the next day. Others may need several sessions before experiencing meaningful change. Response times vary from person to person.
Yes. Because ketamine works through a different mechanism than traditional antidepressants, it can help people who have not responded well to medications or therapy alone.
Ketamine therapy is often recommended for adults, and in some cases older adolescents, whose depression or mood symptoms have not improved with standard treatment. Eligibility depends on your personal and medical history.

TREATMENT OPTIONS & SUPPORT

At Harmony Neurocare, you are never alone during treatment. In your own private room, a dedicated provider remains with you throughout your session, ensuring your experience is safe, supported, and centered on your well-being.
Harmony Neurocare offers intramuscular (IM) ketamine because it provides predictable dosing, consistent absorption, and a more streamlined clinical experience. At this time, we do not offer IV ketamine.
A common protocol is 6 infusions over 2–5 weeks, followed by "booster" sessions as needed.
Possibly. Ketamine can complement your existing treatment plan, but every plan is personalized. Your provider will review your history and coordinate care to ensure ketamine is used safely and effectively.

Pricing depends on the treatment type, dosing, and frequency recommended by your provider. Our team will review your specific plan, discuss costs upfront, and go over any available payment or financing options.

Learn more about the investment for ketamine & SPRAVATO® therapy on our Insurance & Pricing page.

Why Patients Choose Harmony
Neurocare Ketamine and SPRAVATO®

Harmony Neurocare provides a warm, supportive environment with careful monitoring, personalized dosing, and a team experienced in integrating ketamine and SPRAVATO® into broader mental health treatment plans. Your comfort, safety, and long-term healing guide every step of care.

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